907970-13-2

Upstream product

• 194423-80-8 ethyl 3-chloro-6-(trifluoromethyl)quinoxaline-2-carboxylate 
• 5438-70-0 ethyl (4-amino-3,5-dibromophenyl)acetate 
• 907970-08-5 3-(4-ethoxycarbonylmethyl-phenylamino)-6-trifluoromethyl-quinoxaline-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Quinoxaline chemistry. Part 14. 4-(2-Quinoxalylamino)-phenylacetates and 4-(2-quinoxalylamino)-phenylacetyl-L-glutamates as analogues-homologues of classical antifolate agents. Synthesis and evaluation of in vitro anticancer activity

Among a new series of 26 4-(3-substituted-2-quinoxalylamino)phenylacetates and 4-(3-substituted-2-quinoxalylamino)-phenylacetyl-L-glutamates, eight were selected at NCI for evaluation of their in vitro anticancer activity. The results obtained in comparison with the corresponding nor-compounds series seem to indicate that this type of homologation is not helpful.