907994-47-2Relevant academic research and scientific papers
Inhibition of myeloperoxidase: Evaluation of 2H-indazoles and 1H-indazolones
Roth, Aaron,Ott, Sean,Farber, Kelli M.,Palazzo, Teresa A.,Conrad, Wayne E.,Haddadin, Makhluf J.,Tantillo, Dean J.,Cross, Carroll E.,Eiserich, Jason P.,Kurth, Mark J.
, p. 6422 - 6429 (2014)
Myeloperoxidase (MPO) produces hypohalous acids as a key component of the innate immune response; however, release of these acids extracellularly results in inflammatory cell and tissue damage. The two-step, one-pot Davis-Beirut reaction was used to synth
