908003-67-8

Basic information

• Product Name: 6-iodo-2,3-dimethoxyphenylamine
• Synonyms: 6-iodo-2,3-dimethoxyphenylamine
• CAS NO: 908003-67-8
• Molecular Weight: 279.077
• Mol File: 908003-67-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-iodo-2,3-dimethoxyphenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-iodo-2,3-dimethoxyphenylamine(908003-67-8)
• EPA Substance Registry System: 6-iodo-2,3-dimethoxyphenylamine(908003-67-8)

Safety Data

• Hazardous Substances Data: 908003-67-8(Hazardous Substances Data)

Upstream product

• 6299-67-8 2,3-dimethoxyaniline 

Downstream Products

• 1020105-52-5 4-(6-iodo-2,3-dimethoxyphenylamino)-but-2-enoic acid methyl ester 
• 908003-80-5 (6,7-dimethoxy-1H-indol-3-yl)-acetic acid methyl ester 

Relevant articles and documents

Pd-tBuONO Cocatalyzed Aerobic Indole Synthesis

A Pd-tBuONO co-catalyzed scalable and practical synthesis of indoles with molecular oxygen as terminal oxidant is developed. Either terminal or internal 2-vinylanilines could be smoothly converted to desired indoles under one general condition. This method has been evaluated in the large scale synthesis of indomethacin and a potential anti-breast cancer drug candidate 1. (Figure presented.).

Total synthesis of the alkaloid (±)-aspidophytine based on carbonyl ylide cycloaddition chemistry

The RhII-catalyzed cycloaddition cascade of an indolyl-substituted α-diazo imide was used for the total synthesis of the complex pentacyclic alkaloid (±)-aspidophytine. Treatment of the resulting dipolar cycloadduct with BF3·OEt