90802-21-4

Usage

Uses

Used in Chemical Synthesis:
(3-BROMOISOXAZOL-5-YL)METHYLAMINE HYDROCHLORIDE is used as a reagent in chemical synthesis for its ability to facilitate the formation of various organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3-BROMOISOXAZOL-5-YL)METHYLAMINE HYDROCHLORIDE is used as a research compound to aid in the development of new drugs and pharmaceuticals.
Used in Agrochemical Preparation:
(3-BROMOISOXAZOL-5-YL)METHYLAMINE HYDROCHLORIDE is also utilized in the preparation of agrochemicals, contributing to the development of new pesticides and other agricultural chemicals.
Used in Laboratory Environments:
Due to its improved solubility and stability in the hydrochloride salt form, (3-BROMOISOXAZOL-5-YL)METHYLAMINE HYDROCHLORIDE is used in laboratory settings for easier handling and storage.

InChI:InChI=1/C4H5BrN2O.ClH/c5-4-1-3(2-6)8-7-4;/h1H,2,6H2;1H

Upstream product

• 74213-24-4 N-dibromomethylidenehydroxylamine 
• 88067-01-0 N-(propargyl)-dichloroacetamide 
• 105175-04-0 N-(3-Bromo-isoxazol-5-ylmethyl)-2,2-dichloro-acetamide 

Relevant academic research and scientific papers

AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.

Process for the preparation of 3,5-disubstituted isoxazoles

A novel process for the preparation of 3-bromo- and 3-chloro-5-substituted isoxazoles is provided. Dibromo- or dichloro-formaldoxime is reacted with an excess of an 1-alkyne derivative of the formula where R is hydrogen, phenyl or 1-6 C alkyl optionally substituted by halogen, OH, OR', CHO, COR', COOR', CONH2, CONR'R" or NHCOR' where, in turn, R' and R", which may be the same or different, are a 1-6 C alkyl or haloalkyl, in the presence of (i) at least an equimolecular amount, with respect to the dibromo- or dichloro-formaldoxime, of an alkaline base selected from the class consisting of sodium and potassium carbonate and bicarbonate and (ii) an inert solvent in which the 1-alkyne is soluble at room temperature.

A CONVENIENT SYNTHESIS OF MUSCIMOL BY A 1,3-DIPOLAR CYCLOADDITION REACTION

A simple and large scale approach to the synthesis of muscimol 7 has been developed starting from the easily available dibromoformaldoxime 1.