908040-19-7

Upstream product

• 908040-18-6 methyl (S)-4-hydroxy-5-(4-methoxybenzylamino)-5-oxopentanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 562817-52-1 (S)-N-(4-methoxybenzyl)-tetrahydro-5-oxo-2-furancarboxamide 

Downstream Products

• 908040-21-1 (S)-4-(tret-butyldimethylsilyloxy)-5-(4-methoxybenzylamino)-5-oxopentyl methanesulfonate 
• 746663-38-7 (2S,3S)-2-aminocarbonyl-3-hydroxy-1-(4-methoxybenzyl)piperidine 
• 746663-39-8 (2S,3S)-2-cyano-3-hydroxy-1-(4-methoxybenzyl)piperidine 
• 116595-05-2 (2S,3S)-3-hydroxy-2-piperidin-carboxamide 
• 908040-20-0 (S)-2-(tret-butyldimethylsilyloxy)-5-hydroxy-N-(4-methoxybenzyl)pentanamide 

Relevant academic research and scientific papers

Syntheses of enantio-enriched chiral building blocks from l-glutamic acid

Starting from lactone-amide 8, easily derived from l-glutamic acid, enantioselective syntheses of (S)-tetrahydrofuran 2-carboxamide derivative 2 and a protected (S)-3-hydroxypiperidin-2-one (3) are reported. The building block 3 was converted to (2S,3R)-3