90811-87-3Relevant academic research and scientific papers
Efficient synthesis of chalcones by a solid base catalyst
Kantam, M.Lakshmi,Veda Prakash,Venkat Reddy
, p. 1971 - 1978 (2007/10/03)
A simple and efficient heterogeneous procedure has been developed for the synthesis of chalcones (α,β-unsaturated ketones) by the Claisen-Schmidt condensation between arylaldehydes and ketones using Mg-Al-OtBu hydrotalcite (HT-OtBu) as catalyst. Copyright Taylor & Francis, Inc.
Solution phase synthesis of a spiro[pyrrolidine-2,3'-oxindole] library via a three component 1,3-dipolar cycloaddition reaction
Fokas, Demosthenes,Ryan, William J.,Casebier, David S.,Coffen, David L.
, p. 2235 - 2238 (2007/10/03)
A combinatorial library of 26,500 spiro[pyrrolidine,-2,3-oxindoles] was prepared in a single-compound format by a facile intermolecular 1,3-dipolar cycloaddition. An azomethine ylide, generated by the decarboxylative condensation of an isatin 1 with an α-amino acid 2, was trapped by a transchalcone 3 to afford heterocycles of the general structure 4. The regio- and stereochemistry of a representative product was determined by single crystal X-ray structure.
