908242-65-9

Upstream product

• 98796-24-8 2-Amino-2'-fluorodiphenyl Sulfide 
• 615-42-9 1,2-Diiodobenzene 
• 2557-78-0 2-fluorothiophenol 
• 583-53-9 2,3-dibromobenzene 
• 1072-85-1 o-fluorobromobenzene 
• 88-73-3 2-Chloronitrobenzene 
• 98796-23-7 2-fluorophenyl 2-nitrophenyl thioether 

Downstream Products

• 132-65-0 dibenzothiophene 
• 65642-94-6 1-bromodibenzo[b,d]thiophene 
• 135489-54-2 1-phenylthiodibenzothiophene 

Relevant academic research and scientific papers

Reaction method of thiophenol and O-diiodobenzene

The invention discloses a reaction method of thiophenol and o-diiodobenzene. The method comprises the following steps: taking thiophenol and o-diiodobenzene as substrates, reacting in a solvent in the presence of a metal hydride, and completing the reaction of thiophenol and o-diiodobenzene to obtain o-iodobenzene sulfide. Under the action of NaH, o-diiodobenzene and thiophenol are subjected to a nucleophilic reaction to generate an o-iodobenzene sulfide product. According to the method, C-S bond coupling is completed without transition metal participation, operation is easy and convenient, and the problems of metal reagent residues, pollution and the like are solved; meanwhile, compared with an existing precursor, o-diiodobenzene is low in price and convenient to prepare, and has better atom economy; and an iodine exists at the ortho-position of the generated product phenyl sulfide, other conversions can be conveniently carried out to obtain various 1, 2-substituted benzene, and particularly, the excellent yield can be obtained by only needing 3 equivalents of metal hydride.

Preparation method of phenyl sulfide compound

The invention discloses a preparation method of a phenyl sulfide compound, which comprises the following steps: by taking thiophenol and o-diiodobenzene as substrates, reacting in a solvent in the presence of a metal hydride to obtain iodine-containing phenyl sulfide; the iodine-containing phenyl sulfide can be subjected to intramolecular reaction to obtain a phenyl sulfide compound; or the iodine-containing phenyl sulfide can react with other raw materials to obtain the phenyl sulfide compound. The ortho-iodine compound prepared by the invention has great application value, can be further widely converted, can be subjected to coupling reaction with phenylboronic acid, thiophenol, phenylacetylene and the like under the catalysis of Pd to prepare various 2-substituted thiophenol, and has important significance in material science and pharmaceutical synthesis.

Short syntheses of 1-substituted dibenzothiophene derivatives

The 1-substituted dibenzothiophene motif is an unusual substitution pattern that has previously been accessedviaa multi-step synthesis. We demonstrate a simple one-pot preparation of 1-lithiodibenzothiophene from commercial materialsviaa cascade of two benzyne additions and conversion to several derivatives by addition of electrophiles. A chiral amine containing the 1-dibenzothiophene motif was also prepared. This work avoids the use of precious metals ortert-butyllithium and is much shorter and more convenient than existing routes to 1-substituted dibenzothiophenes.

Compound Containing At Least Two 5-Membered Heterocycle And Organic Electronic Element Using The Same, Terminal Thereof

The present invention refers to 2 has a compound having a heterocyclic user one or more five won and electrical component, provides terminal with.

A route to regioselectively functionalized carbazoles, dibenzofurans, and dibenzothiophenes through anionic cyclization of benzyne-tethered aryllithiums

The treatment of 2-fluorophenyl 2-iodophenylamines, ether, and thioether, easily prepared from commercially available products, with 3.3 equiv of t-BuLi and further reaction with selected electrophiles gives rise to functionalized carbazole, dibenzofuran, and dibenzothiophene derivatives in a direct and regioselective manner. The process involves an anionic cyclization on a benzyne-tethered aryllithium intermediate.