908252-37-9Relevant academic research and scientific papers
A new method for the synthesis of multisubstituted pyrroles of biological interest by double nucleophilic addition to α,β-unsaturated imines
Takahashi, Atsushi,Kawai, Shiho,Hachiya, Iwao,Shimizu, Makoto
, p. 191 - 200 (2010)
Double nucleophilic addition reactions of dialkoxy ketene silyl acetals proceeded with α,β-unsaturated imines to give 1,4-and 1,2-double addition products, and their subsequent transformations afforded multisubstituted pyrroles in good yields. Application
Efficient pyrrole synthesis using double nucleophilic addition to α,β-unsaturated imines with plural nucleophiles
Shimizu, Makoto,Takahashi, Atsushi,Kawai, Shiho
, p. 3585 - 3587 (2007/10/03)
2,3,5-Trisubstituted pyrroles were prepared in a regioselective manner using the double nucleophilic addition of α,α-dialkoxy ketene silyl acetals and ketene sily thioacetals or trimethylsilyl cyanide to α,β-unsaturated !mines followed by acid-promoted cy
