908255-02-7Relevant academic research and scientific papers
Asymmetric cycloetherification of in situ generated cyanohydrins through the concomitant construction of three chiral carbon centers
Kurimoto, Yosuke,Nasu, Teruhisa,Fujii, Yuki,Asano, Keisuke,Matsubara, Seijiro
supporting information, p. 2156 - 2160 (2019/03/26)
The organocatalytic enantio- A nd diastereoselective cycloetherification of in situ generated cyanohydrins through the concomitant construction of three chiral carbon centers is reported. This protocol facilitates the concise synthesis of optically active
Synthesis and reactivity of imide-derived bisvinyl phosphates. Reactivity of 2,6-disubstituted 1,4-dihydropyridines
Mousset, Deborah,Gillaizeau, Isabelle,Sabatie, Andrea,Bouyssou, Pascal,Coudert, Gerard
, p. 5993 - 5999 (2007/10/03)
Symmetrical and unsymmetrical 2,6-disubstituted dihydropyridines were prepared in high yields under mild conditions using the Suzuki and Stille Pd-catalyzed coupling reactions of imide-derived bisvinyl phosphates with a range of aryl, heteroaryl, and alkenyl moieties. The alkylation reaction at C-4 easily afforded original tri- and tetrasubstituted dihydropyridines. Hydrolysis of the latter under acidic condition provided efficiently either open-chain 1,5-diketones or di- or trisubstituted pyridines.
