908292-41-1Relevant academic research and scientific papers
Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity
Biava, Mariangela,Porretta, Giulio Cesare,Poce, Giovanna,Supino, Sibilla,Deidda, Delia,Pompei, Raffaello,Molicotti, Paola,Manetti, Fabrizio,Botta, Maurizio
, p. 4946 - 4952 (2007/10/03)
On the basis of suggestions derived either from a pharmacophoric model for antitubercular agents or from a structure-activity relationship analysis of many pyrroles previously described by us, we report here the design and synthesis of new analogues of 1,
DERIVATIVES OF 1-{ [1,5-BIS(4-CHLOROPHENYL)-2-METHYL-1H-PYRROL-3-YL] METHYL}-4- METHYLPIPERAZINE, SYNTHESIS PROCESS AND USES THEREOF
-
Page/Page column 8; 10, (2008/06/13)
The present invention concerns pyrrole compounds, derivatives of 1-{[1,5-bis(4- chlorophenyl)-2-methyl-lH-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents having high activi
