90833-59-3Relevant academic research and scientific papers
Room-temperature free-radical-induced polymerization of 1,1′-(methylenedi-1,4-phenylene)bismaleimide via a novel diphenylquinoxaline-containing hyperbranched aromatic polyamide
Baek, Jong-Beom,Ferguson, John B.,Tan, Loon-Seng
, p. 4385 - 4396 (2003)
Two new diphenylquinoxaline-containing AB2 monomers, 2,3-bis(4-aminophenyl)quinoxaline-6-carboxylic acid, 5 and 2,3-bis[4-(4-aminophenoxy)phenyl]quinoxaline-6-carboxylic acid, 9 were prepared and polymerized via the Yamazaki reaction to form th
Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors
You, Lei,Cho, Eun Jeong,Leavitt, John,Ma, Li-Chung,Montelione, Gaetano T.,Anslyn, Eric V.,Krug, Robert M.,Ellington, Andrew,Robertus, Jon D.
supporting information; experimental part, p. 3007 - 3011 (2011/06/24)
A library of quinoxaline derivatives were prepared to target non-structural protein 1 of influenza A (NS1A) as a means to develop anti-influenza drug leads. An in vitro fluorescence polarization assay demonstrated that these compounds disrupted the dsRNA-NS1A interaction to varying extents. Changes of substituent at positions 2, 3 and 6 on the quinoxaline ring led to variance in responses. The most active compounds (35 and 44) had IC50 values in the range of low micromolar concentration without exhibiting significant dsRNA intercalation. Compound 44 was able to inhibit influenza A/Udorn/72 virus growth.
Bis-(ortho-aminophenol)-carboxylic acid AB2 monomer
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, (2008/06/13)
An AB2monomer of the formula: wherein Z is selected from the group consisting of —OH, —SH and —NH2HCl, is useful for the preparation of hyperbranched polybenzoxazoles.
Quinoxaline-containing AB2 monomers for hyperbranched aromatic polyamides
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, (2008/06/13)
AB2monomers of the formula wherein Q is Polymerization of these monomers results in hyperbranched aromatic polyamides.
