908341-13-9Relevant academic research and scientific papers
Synthesis and Characterization of Hairpin Mimics that Modulate the Early Oligomerization and Fibrillization of Amyloid β-Peptide
Vahdati, Leila,Kaffy, Julia,Brinet, Dimitri,Bernadat, Guillaume,Correia, Isabelle,Panzeri, Silvia,Fanelli, Roberto,Lequin, Olivier,Taverna, Myriam,Ongeri, Sandrine,Piarulli, Umberto
, p. 2971 - 2980 (2017)
Alzheimer's disease is a neurodegenerative disorder that is linked to oligomerization and fibrillization of different amyloid β-peptide isoforms. Among these amyloid peptides, Aβ1–42 is considered the most aggregative and neurotoxic species. We
Molecular tongs containing amino acid mimetic fragments: New inhibitors of wild-type and mutated HIV-1 protease dimerization
Bannwarth, Ludovic,Kessler, Albane,Pèthe, St?phanie,Collinet, Bruno,Merabet, Na?ma,Boggetto, Nicole,Sicsic, Sames,Reboud-Ravaux, Michèle,Ongeri, Sandrine
, p. 4657 - 4664 (2007/10/03)
We have designed, synthesized, and evaluated the inhibitory activity and metabolic stability of new peptidomimetic molecular tongs based on a naphthalene scaffold for inhibiting HIV-1 protease dimerization. Peptidomimetic motifs were inserted into one pep
