90839-16-0

Upstream product

• 5694-92-8 4-[2-(4-hydroxybutyl)[1,3]dioxolan-2-yl]butan-1-ol 
• 109-99-9 tetrahydrofuran 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 5851-37-6 4-(phenylthio)butan-1-ol 
• 31608-22-7 4-bromo-1-(2-tetrahydropyranyloxy)butane 
• 96754-03-9 2-(phenylsulfonyl)tetrahydro-2H-pyran 
• 92511-12-1 1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane 
• 89455-85-6 2-<4'-(tetrahydro-2H-pyran-2-yl)oxy butan>-5,6-dihydro-4H-pyran 
• 89455-90-3 C₁₄H₂₄O₃ 
• 125104-01-0 N,N-Dimethyl-N'-{5-(tetrahydro-pyran-2-yloxy)-1-[4-(tetrahydro-pyran-2-yloxy)-butyl]-pentylidene}-hydrazine 
• 113586-33-7 7,9-Dioxa-1,4-dithia-dispiro[4.2.5.2]pentadecane 
• 13178-64-8 2-(4-hydroxy-n-butyl) tetrahydropyran ether 
• 616240-05-2 1-benzyloxy-9-hydroxy-non-3-yn-5-one 
• 113297-14-6 1,7-dioxaspiro<5.5>undec-4-ene 

Relevant academic research and scientific papers

Tosmic in the preparation of spiroacetals: Synthesis of pheromone components of olive fruit fly

The dialkylated tosylmethyl isocyanide derivatives obtained by alkylation of TosMIC with halohydrin derivatives, on hydrolysis lead to the formation of 1,7-dioxaspiroalkanes.

Compact chiral environment biphenanthrene skeleton chiral phosphoric acid and preparation method and application thereof

The invention discloses a diphenanthrene skeleton chiral phosphoric acid with a tight chiral environment, a preparation method thereof, and an application of the diphenanthrene skeleton chiral phosphoric acid as a catalyst in asymmetric synthesis of a chiral spiro ketal derivative. The chiral catalyst shows good catalytic activity and enantioselectivity in a reaction for asymmetrically synthesizing spiro ketal, and has a good industrial application prospect. The invention belongs to the field of asymmetric synthetic chemistry.

A new short synthesis of (±)-olean through cross metathesis

A new synthesis of (±)-1,7-dioxaspiro[5.5]undecane (olean), the olive fruit fly pheromone, utilizing the cross-metathesis reaction as the key-step, is reported.

Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals

The design, synthesis, and validation of new highly effective bifunctional linchpins for type II anion relay chemistry (ARC) has been achieved. The mechanistically novel negative-charge migration that comprises the Brook rearrangement is now initiated by a stabilized tetrahedral intermediate, which is generated by nucleophilic addition to a Weinreb amide, rather than by a simple oxyanion that is generated from an epoxide. As a result, the linchpin preserves the carbonyl functionality in the ARC adducts, thus permitting access to functionally complex systems in a single flask without the need for further chemical manipulations. This tactic was validated with the one-pot preparation of monoprotected 1,3-diketones as well as pyran and spiroketal scaffolds, depending on the choice of nucleophile, electrophile, and work-up conditions.

Chiral imidodiphosphates and derivatives thereof

The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Br?nsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.

CHIRAL IMIDODIPHOSPHATES AND DERIVATIVES THEREOF

The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Br?nsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.

Synthesis of donor-σ-perylenebisimide-acceptor molecules having PEG swallowtails and sulfur anchors

Donor-σ-Acceptor (D-σ-A) molecules, arrayed in a monolayer between electrodes, can serve as molecular rectifiers. Using perylene-3,4,9,10-tetracarboxylic bisimide (PBI) as the acceptor allows the attachment of the donor group to one imide nitrogen and a solubilizing swallowtail, normally a long (e.g., C19) alkane connected at midchain, on the other. Such an alkyl tail facilitates the formation of Langmuir-Blodgett (LB) monolayers. We have employed several modified swallowtails to make new D-σ-A molecules: poly(ethylene glycol) (PEG) swallowtails with 6 ether oxygens or with 4 ether oxygens to promote hydrophilicity in orienting LB monolayers, and alkyl swallowtails ending with sulfur anchors (thioacetate, thiol, or methyl disulfide) to stabilize attachment of the D-σ-A molecules to gold electrodes. The preparation and characterization of D-σ-A molecules containing combinations of these swallowtails with pyrene, ferrocene, and tetramethylphenylenediamine donor groups is described.

A highly efficient access to spiroketals, mono-unsaturated spiroketals, and furans: Hg(II)-catalyzed cyclization of alkyne diols and triols

Hg(II) salts are identified as highly efficient catalysts for the versatile construction of spiroketals from alkyne diols in aqueous conditions. Monounsaturated spiroketals and furans were accessed with equal ease when propargylic triols (or propargylic d

Highly efficient catalytic routes to spiroketal motifs

The versatile and efficient synthesis of a variety of spiroketal motifs via the double intramolecular hydroalkoxylation of aliphatic and aromatic alkyne diols was achieved using simple and readily accessible Ir(I) and Rh(I) cyclooctadiene complexes as cat

Metal-catalyzed regioselective oxy-functionalization of internal alkynes: An entry into ketones, acetals, and spiroketals

(Chemical Equation Presented) Platinum(II) and an unusual cationic gold(I) complex were identified as mild catalysts for the room temperature cycloisomerization or tandem hydroalkoxylation/acetal formation of unactivated internal alkynols. Under the appro