90839-68-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid is used as a building block for the synthesis of various pharmaceuticals due to its unique structural features and potential therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(3-chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid is utilized as a key component in the development of agrochemicals, leveraging its potential antifungal and antibacterial properties to protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
1-(3-chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid is employed as a common reagent in organic synthesis, where its versatility and structural features contribute to the creation of a wide range of chemical compounds.
Used in Chemical Research:
As a valuable compound in chemical research, 1-(3-chlorophenyl)-1H-1,2,4-triazole-3-carboxylic acid is used to explore new chemical reactions, mechanisms, and applications, further expanding the understanding of its properties and potential uses.

Upstream product

• 63503-60-6 3-chlorophenylboronic acid 
• 863609-11-4 1-(3-chloro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid methyl ester 

Downstream Products

• 1443758-32-4 {4-[1-(3-chloro-phenyl)-1H-[1,2,4]triazole-3-carbonyl]-2,2-dimethyl-piperazin-1-yl}-(6-methoxy-pyridin-2-yl)-methanone 
• 1443758-33-5 {4-[1-(3-chloro-phenyl)-1H-[1,2,4]triazole-3-carbonyl]-2-ethyl-piperazin-1-yl}-(6-methoxy-pyridin-2-yl)-methanone 
• 1443758-76-6 (S)-{4-[1-(3-chloro-phenyl)-1H-[1,2,4]triazole-3-carbonyl]-3-methyl-piperazin-1-yl}-(6-methoxy-pyridin-2-yl)-methanone 
• 1443758-77-7 (R)-{4-[1-(3-chloro-phenyl)-1H-[1,2,4]triazole-3-carbonyl]-3-methyl-piperazin-1-yl}-(6-methoxy-pyridin-2-yl)-methanone 

Relevant academic research and scientific papers

Monoacylglycerol Lipase Modulators

Bridged compounds of Formula (I) and Formula (II), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, bipolar disorder), cancers and eye conditions. wherein R2, R3 R4, R5 and R6 are defined herein.

PIPERAZINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLU5 RECEPTORS

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.