90840-02-1

Basic information

• Product Name: 1H-Pyrazol-3-amine, 1-(2-methoxyphenyl)-
• CAS NO: 90840-02-1
• Molecular Formula: C10H11N3O
• Molecular Weight: 189.217
• Mol File: 90840-02-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-3-amine, 1-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-3-amine, 1-(2-methoxyphenyl)-(90840-02-1)
• EPA Substance Registry System: 1H-Pyrazol-3-amine, 1-(2-methoxyphenyl)-(90840-02-1)

Safety Data

• Hazardous Substances Data: 90840-02-1(Hazardous Substances Data)

Usage

Structure

A derivative of pyrazol-3-amine with a 2-methoxyphenyl group attached to the 1-position

Potential applications

Medicinal chemistry, building block for the synthesis of other organic molecules

Safety

Handle with care, follow proper safety protocols, potential hazards associated with handling and use.

Upstream product

• 1820-80-0 3-aminopyrazole 
• 529-28-2 4-iodoanisol 

Relevant articles and documents

Copper(I)/Copper(II)-Assisted Tandem Catalysis: The Case Study of Ullmann/Chan-Evans-Lam N1,N3-Diarylation of 3-Aminopyrazole

Unprecedented CuI/CuII-assisted tandem catalysis allowing an Ullmann/Chan-Evans-Lam sequence was achieved. This three-component, one-pot reaction triggered by a change in the oxidation state of the metal leads to the selective N1,N3-diarylation of 3-aminopyrazole. This new method should be a valuable tool for small-molecule drug discovery that requires suitable regio- and/or chemoselective strategies for the N-arylation of nitrogen-containing heterocycles. Tandem power: The first assisted tandem copper-catalyzed process, triggered by a change in the oxidation state of the metal, is developed to allow a one-pot Ullman/Chan-Evans-Lam sequence leading to the selective N1,N3-diarylation of 3-aminopyrazole.