90861-96-4Relevant academic research and scientific papers
Tetrahydrobenzo[c]thieno[2,1-e]isothiazole 4-Oxides: Three-Dimensional Heterocycles as Cross-Coupling Building Blocks
Lamers, Philip,Bolm, Carsten
supporting information, p. 116 - 118 (2018/01/17)
Unprecedented three-dimensional heterocycles are introduced, and their scaffold functionalization is described. A robust synthetic method utilizing cheap commercially available starting materials leads to a wide range of products on gram scale. The product portfolio can be expanded by applying newly devised building blocks with relevance for automated parallel synthesis in cross-coupling reactions.
Thermal Reaction of Arylnitrenes with Dimethyl Sulphide, Thioanisole, and Tetrahydrothiophene
Benati, Luisa,Montevecchi, P. Carlo,Spagnolo, Piero
, p. 625 - 627 (2007/10/02)
The thermal decomposition of the aryl azides (1) into dimethyl sulphide (2), thioanisole (3), and tetrahydrothiophene (4) generally affords the 2-substituted anilines (5)-(7) in practicable yields by Sommelet-Hauser rearrangement of the intermediate N-arylsulphimides (11a-c) which result from arylnitrene attack at the sulphur atom of (2)-(4).This constitutes a potential synthetic procedure.
