90878-20-9Relevant articles and documents
Imidazoline derivatives as alpha-1A adrenoceptor ligands
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Page/Page column 26, (2010/02/11)
Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.
Derivatives of Phenylurea as Antagonists of Mice, Rat, Guinea Pig, and Rabbit 5-HT3 Receptors
Hansen, John Bondo,Christensen, Birgitte,Weiss, Jan,Suzdak, Peter D.,Sheardown, Malcolm J.,et al.
, p. 308 - 315 (2007/10/03)
1,2,4-Oxadiazolyl- and O-alkyloximinomethyl-substituted phenylureas equipotently bind to 5-HT3 receptors from different species in vitro in contrast to the normal 10-100 fold lower affinity for guinea pig ileal receptors. Compared to the in vitro receptor