908836-41-9

Upstream product

• 87-42-3 6-chloro-7H-purine 
• 908836-37-3 Acetic acid (2R,3R,4R,5R)-4-acetoxy-3,5-bis-benzyloxymethyl-2-(6-chloro-purin-9-yl)-tetrahydro-furan-3-yl ester 
• 908836-45-3 (2R,3R,4R,5R)-3,5-Bis-benzyloxymethyl-2-(6-chloro-purin-9-yl)-tetrahydro-furan-3,4-diol 
• 60-24-2 2-hydroxyethanethiol 
• 908836-50-0 (2R,3R,4R,5R)-3,5-Bis-benzyloxymethyl-2-[6,6-bis-(2-hydroxy-ethylsulfanyl)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-3,4-diol 

Relevant academic research and scientific papers

Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents

On the basis of potent anti-HCV activity of 2′-C-methyladenosine, novel 2′-C-hydroxymethyladenosine analogues 2a-c were synthesized from d-ribose in order to lead to favorable interaction with HCV polymerase. Among compounds tested, adenosine derivative 2