908848-10-2Relevant academic research and scientific papers
NASAL VACCINE
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Page/Page column 21-22, (2008/06/13)
The present invention provides a nasal vaccine capable of intranasally inducing an effective immunity reaction. Specifically, the invention provides a nasal vaccine containing a compound having an NKT cell-activating action, particularly a compound repres
RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines
Fuhshuku, Ken-ichi,Hongo, Naomi,Tashiro, Takuya,Masuda, Yui,Nakagawa, Ryusuke,Seino, Ken-ichiro,Taniguchi, Masaru,Mori, Kenji
, p. 950 - 964 (2008/09/17)
Conformationally restricted analogues of KRN7000, an α-d-galactosyl ceramide, were synthesized to examine their bioactivity for mouse natural killer (NK) T cells to produce cytokines. RCAI-8, 9, 51, and 52 are the analogues with a pyrrolidine ring, and RC
COMPOUND HAVING CYCLIC STRUCTURE AND USE THEREOF
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Page/Page column 19-20, (2008/06/13)
The present invention relates to a compound represented by the following formula (1') wherein R is an aldopyranose residue, R2 is a C2-18 hydrocarbon group optionally having substituent(s), R3 is an acyl group, X is an oxygen atom, a
