909034-84-0

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 103-81-1 Benzeneacetamide 
• 50-00-0 formaldehyd 
• 15142-89-9 1‘-benzyl-2H-spiro[isoquinoline-1,4’-piperidin]-3(4H)-one 
• 909034-83-9 1'-benzyl-2-methyl-3,4-dihydro-2H-spiro[isoquinoline-1,4'-piperidin]-6-yl trifluoromethanesulfonate 

Relevant academic research and scientific papers

TRPML MODULATORS

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

SPIRO-ISOQUINOLINE-1,4'-PIPERIDINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to spiro-isoquinoline-1,4'-piperidine compounds having dual pharmacological activity towards both the sigma (σ) receptor and the μ-opiod receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR USE AS OXYTOCIN ANTAGONISTS

The present invention relates to a class of substituted triazoles of formula (I), uses thereof, and compositions containing said compounds. These compounds have activity as oxytocin antagonists.