909115-19-1Relevant articles and documents
Epimerization free synthesis of O-acyl isodipeptides employing COMU
Samarasimhareddy,Hemantha, Hosahalli P.,Ananda, Kuppanna,Sureshbabu, Vommina V.
experimental part, p. 406 - 410 (2012/07/17)
O-Acyl isodipeptides are prepared by coupling Boc-Ser/Thr-OBzl with Fmoc-Xaa-OH employing COMU, well known third generation peptide coupling agent. The reaction proceeds with high yield and the chemical homogeneity of the synthesized molecules were establ
Depsipeptide methodology for solid-phase peptide synthesis: Circumventing side reactions and development of an automated technique via depsidipeptide units
Coin, Irene,Doelling, Rudolf,Krause, Eberhard,Bienert, Michael,Beyermann, Michael,Sferdean, Calin Dan,Carpino, Louis A.
, p. 6171 - 6177 (2007/10/03)
The depsipeptide technique is a recently developed method for peptide synthesis which is applicable to difficult sequences when the synthetic difficulty arises because of aggregation phenomena. In the present work, application of the depsipeptide method t