909262-73-3Relevant academic research and scientific papers
Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent
Ugwu, David I.,Okoro, Uchechukwu C.,Mishra, Narendra K.
, p. 110 - 116 (2018)
Thousands of death in Africa and other developing nations are still attributed to trypanosomiasis. Excessive sleep has been associated with increased inflammation. We report herein, the synthesis, antitrypanosomal and anti-inflammatory activities of eight
Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies
Ugwu, David Izuchukwu,Okoro, Uchechukwu Christopher,Ukoha, Pius Onyeoziri,Okafor, Sunday N.,Gupta, Astha
, p. 405 - 415 (2018/03/21)
Twelve new derivatives of benzothiazole bearing benzenesulphonamide and carboxamide were synthesised and investigated for their in vivo anti-inflammatory, analgesic and ulcerogenic activities. Molecular docking showed an excellent binding interaction of t
Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
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, (2008/06/13)
(R,R)-2,5-Diazabicyclo[ 2.2.1]heptanes are prepared from a compound of the formula STR1 wherein X and R2 are as defined herein, by heating with tosylchloride in pyridine, reacting the formed compound of the formula STR2 with a C1 -C6 alkylamine or ammonia, and reducing or hydrolyzing the formed compound of the formula STR3 wherein R1 is hydrogen or C1 -C6 alkyl.
Agents for treatment of brain ischemia
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, (2008/06/13)
A series of 5-halopyrimidin-2-ylpiperazinylalkyl derivatives having useful anti-ischemic properties for treatment and prevention of dirorders resulting from brain and/or spinal cord anoxia.
