90968-56-2Relevant academic research and scientific papers
Synthesis of 1-(2-Aminovinyl)indoles and 1,3′-Biindoles by Reaction of 2,2-Diaryl-Substituted 2 H-Azirines with α-Imino Rh(II) Carbenoids
Khaidarov, Adel R.,Rostovskii, Nikolai V.,Zolotarev, Andrey A.,Khlebnikov, Alexander F.,Novikov, Mikhail S.
, p. 3743 - 3753 (2019/02/14)
An effective and operationally simple method for the preparation of 1-(2-(sulfonamido)vinyl)indoles (SAV-indoles) by the Rh(II)-catalyzed reaction of 2,2-diaryl-2H-azirines with 1-sulfonyl-1,2,3-triazoles has been developed. This method enables the stereo
An unexpected disproportional reaction of 2H-azirines giving (1E,3Z)-2-aza-1,3-dienes and aromatic nitriles in the presence of nickel catalysts
Okamoto, Kazuhiro,Mashida, Ayano,Watanabe, Masahito,Ohe, Kouichi
supporting information; experimental part, p. 3554 - 3556 (2012/06/18)
An unprecedented nickel-catalysed disproportional reaction of 2,3-diaryl-2H-azirines forming azabutadienes and aromatic nitriles was discovered. This reaction involves the cleavage of two bonds of the 2H-azirine framework, which provides a novel type of transformation of 2H-azirines.
Fe(II)-catalyzed amination of aromatic C-H bonds via ring opening of 2 H-azirines: Synthesis of 2,3-disubstituted indoles
Jana, Samaresh,Clements, MacK D.,Sharp, Barry K.,Zheng, Nan
supporting information; experimental part, p. 3736 - 3739 (2010/11/03)
A general method for the synthesis of 2,3-disubstituted indoles is described. The key feature of this method is the amination of aromatic C-H bonds via FeCl2-catalyzed ring opening of 2H-azirines. The method tolerates a variety of functional groups such as Br, F, NO2, OMe, CF3, OTBS, alkenes, and OPiv. The method can also be extended to synthesize azaindoles.
Steady-State and Laser Photolysis Studies of Substituted 2H-Azirines. Spectroscopy, Absolute Rates, and Arrhenius Behavior for the Reaction of Nitrile Ylides with Electron Deficient Olefins
Padwa, Albert,Rosenthal, Robert J.,Dent, William,Filho, Pedro,Turro, Nicholas J.,et al.
, p. 3174 - 3180 (2007/10/02)
The photobehavior of 2,2-diphenyl-3-methyl-2H-azirine (15) and 2-methyl-2,3-diphenyl-2H-azirine (14) was investigated in solution at 298 K.Both azirines undergo ready ring opening on exposure to UV light to give nitrile ylides which can be trapped with me
