909730-00-3Relevant academic research and scientific papers
Progress toward the synthesis of piperazimycin A: exploration of the synthesis of γ-hydroxy and γ-chloropiperazic acids
Phillip Kennedy,Brogan, John T.,Lindsley, Craig W.
, p. 4116 - 4118 (2008/09/21)
Employing Hamada's chemistry with MAOS optimization of several steps, an expedient route to key (3S,5S)- and (3R,5R)-γ-hydroxy and (3R,5S)-γ-chloropiperazic acids, was developed en route to a total synthesis of piperazimycin A.
The efficient synthesis of (3R,5R)-5-hydroxypiperazic acid and its diastereomer using Lewis acid-promoted diastereoselective Strecker synthesis
Makino, Kazuishi,Jiang, Hang,Suzuki, Tatsuya,Hamada, Yasumasa
, p. 1644 - 1649 (2007/10/03)
The stereoselective synthesis of (3R,5R)-5-hydroxypiperazic acid, a component of naturally occurring antibiotic cyclodepsipeptides, and its diastereomer was achieved via the use of Lewis acid-promoted diastereoselective Strecker synthesis as a key step, i
