90994-68-6Relevant academic research and scientific papers
A Crystallographic Study related to Intramolecular Hydride Shifts in Polycyclic Hydroxyketones
Cernik, Robert V.,Craze, Gabrielle-Anne,Mills, Owen S.,Watt, Ian,Whittleton, Stephen N.
, p. 685 - 690 (2007/10/02)
The crystal structures of the p-nitrobenzoate (p-NB) esters of the hydroxyketones (1)-(3) have been determined.These contain imbedded boat-conformation 4-hydroxycyclohexanones whose C(1)-C(4) distances decrease from 2.67(3) Angstroem in (1) (R = p-NB) to 2.479(6) Angstroem in (3) (R = p-NB).The relationship of the structural variation to the barriers and reaction path for the 1,4-hydride transfer in the corresponding alkoxide anions is discussed.
