91-53-2 Usage
Description
Ethoxyquin is used as an antioxidant in animal feed
and caused contact dermatitis in a worker at an animal
feed mill.
Chemical Properties
Different sources of media describe the Chemical Properties of 91-53-2 differently. You can refer to the following data:
1. Yellow liquid.Discolors and stains badly.
2. Transparent yellow or brown viscous liquid.
Uses
Different sources of media describe the Uses of 91-53-2 differently. You can refer to the following data:
1. Antioxidant in feed and food; antidegradation agent for rubber.
2. Antifungal
3. Ethoxyquin is an antioxidant used in the preservation of color in
chili powder, ground chili, and paprika.
Definition
ChEBI: A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.
General Description
Clear light yellow to dark brown viscous liquid. Discolors and stains badly. Mercaptan-like odor.
Air & Water Reactions
Polymerizes and darkens in color on exposure to light and air. Insoluble in water.
Reactivity Profile
Ethoxyquin may undergo a hazardous polymerization at temperatures above 320° F. Tends to polymerize and darken in color on exposure to light and air. Not compatible with oxidizing agents and with strong acids .
Hazard
Toxic by ingestion.
Fire Hazard
Ethoxyquin is combustible.
Agricultural Uses
Insecticide, Fungicide, Plant growth regulator,
Ingredient in other products: Used for preharvest or postharvest preservation of
color in apples and pears. It is used as an antioxidant to
preserve color in paprika and ground and powdered chili.
Ethoxyquin is also a chemical preservative used in animal
feed to prevent ingredients from reacting with oxygen and
becoming rancid. It has been known to cause birth defects
in pet birds and dogs. Not approved for use in EU countries[
115]. Registered for use in the U.S.
Trade name
CHEMLEY?[C]; DECCOQUIN
305?; EMQ?; EQ?; NIFLEX?; NIX-SCALD?[C];
SANTOFLEX A?; SANTOFLEX AW?; SANTOQUIN?;
SANTOQUINE?; STOP-SCALD?
Contact allergens
Ethoxyquin is used as an antioxidant in animal feed
and caused contact dermatitis in a worker at an animal
feed mill
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes of NOx.
Potential Exposure
Quinoline insecticide, fungicide and
plant growth regulator. Also and ingredient in other products. Used for preharvest or postharvest preservation of
color in apples and pears. It is used as an anti-oxidant to
preserve color in paprika and ground and powdered chili.
Ethoxyquin also is a chemical preservative used in animal
feed to prevent ingredients from reacting with oxygen and
becoming rancid. It has been known to cause birth defects
in pet birds and dogs
Purification Methods
Purify Ethoxyquin by fractional distillation in vacuo whereby the distillate solidifies to a glass. [Knoevenagel Chem Ber 54 1723, 1730 1921.] The methiodide has m 179o (from EtOH), and the 1-phenylcarbamoyl derivative has m 146-147o (from EtOH). [Beaver et al. J Am Chem Soc 79 1236 1957, Beilstein 21 III/IV 95.]
Incompatibilities
Polymerization can occur on contact
with strong light and/or water. Decomposes in temperatures
above 150℃. Keep away from oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); strong acids.
Waste Disposal
Do not discharge into drains
or sewers. Dispose of waste material as hazardous waste
using a licensed disposal contractor to an approved landfill.
Consult with environmental regulatory agencies for
guidance on acceptable disposal practices. If allowed,
Incineration with effluent gas scrubbing is recommended.
Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your
regional EPA office
Check Digit Verification of cas no
The CAS Registry Mumber 91-53-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91-53:
(4*9)+(3*1)+(2*5)+(1*3)=52
52 % 10 = 2
So 91-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3
91-53-2Relevant articles and documents
Novel compound and application thereof in preparation of medicine for treating cancer
-
Paragraph 0114-0116, (2021/10/11)
The invention provides a novel compound and application thereof in preparation of a medicament for treating cancer. The compound has the activity of promoting PSGR expression in the prostate cancer cells, can activate PSGR signals, has the effect of inhibiting the proliferation of prostate cancer cells, is expected to be applied to treating prostatic cancer in the future and is a potential medicine for treating prostatic cancer. In addition, the inventors have unexpectedly found that compounds satisfying the above conditions have been expected to have activity to inhibit proliferation of breast cancer cells and ovarian cancer cells in addition to the activity of inhibiting proliferation of prostate cancer cells, and are expected to be potential drugs for treating breast cancer and ovarian cancer. A wide clinical application prospect is shown.
A surface-active ionic liquid catalyst used for the synthesis of ethoxy quinoline (by machine translation)
-
Paragraph 0019-0026, (2019/10/23)
The invention relates to a with the surface activity of the ionic liquid catalyst used for the synthesis of ethoxy quinoline, which belongs to the field of chemical synthesis. The activity of the catalyst is the surface of the ionic liquid, the catalyst the catalytic activity is high, good stability, catalytic reaction time is short, the one-way high conversion rate, the catalyst is easy to recovery can be recycled; and the catalyst is also used as a solvent, without additional adding the reaction solvent. The method improves production efficiency, reduces the energy consumption of the production. (by machine translation)
METHOD FOR SYNTHESIZING HIGH PURITY ETHOXYQUIN, HIGH PURITY ETHOXYQUIN SYNTHESIZED BY THE SAME AND ANTIOXIDANT FOR FEED SUPPLEMENT INCLUDING THE SAME
-
Paragraph 0092-0096, (2018/05/15)
The present invention relates to a synthesis method of high-purity ethoxyquin, high-purity ethoxyquin synthesized thereby, and an antioxidant agent for use in a feed additive comprising the same. The synthesis method of high-purity ethoxyquin according to the present invention comprises: (S100) weighing of a first raw material and introduction of the same into a reactor step for weighing a first raw material and introducing the first raw material into a reactor; (S200) a heating step for heating the reactor in which the first raw material and a catalyst have been introduced; (S300) a second raw material introduction and reaction step for introducing a second raw material into the heated reactor to conduct a reaction of the first raw material and the second raw material; (S400) a cooling, neutralization and separation step for cooling and neutralizing a product produced from progression of the reaction inside the reactor and separating the product; and (S500) a distillation step for distilling the separated product to produce an ethoxyquin monomer. Through the above configuration, the antioxidant agent for use in a feed additive comprising high-purity ethoxyquin according to the present invention can prevent nutrients from being destroyed due to fatty acid oxidation; prevents degradation of nutrients due to storage of raw materials, and distribution and storage of a feed to prevent degradation in quality of the feed; and maintain the quality and freshness of the feed uniformly for a long time.(S100) Weighing of a first raw material and introduction of the same into a reactor step(S200) Heating step(S300) Second raw material introduction and reaction step(S400) Cooling, neutralization and separation step(S500) Distillation stepCOPYRIGHT KIPO 2018