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Usage

Uses

Used in Research and Development:
m-Tolyldiethanolamine is used as a research chemical for various scientific and industrial applications. Its unique properties make it a valuable compound for exploring new chemical reactions and developing innovative products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, m-Tolyldiethanolamine is used as an intermediate in the synthesis of various drugs and active pharmaceutical ingredients. Its ability to form stable complexes with other molecules makes it a promising candidate for drug development.
Used in Cosmetics Industry:
m-Tolyldiethanolamine is used as a stabilizer and emulsifier in the cosmetics industry. Its ability to improve the texture and consistency of cosmetic products makes it an essential component in the formulation of creams, lotions, and other skincare products.
Used in Agrochemical Industry:
In the agrochemical industry, m-Tolyldiethanolamine is used as a precursor in the synthesis of various agrochemicals, such as pesticides and herbicides. Its versatility in chemical reactions allows for the development of effective and targeted agrochemical products.
Used in Fine Chemicals Industry:
m-Tolyldiethanolamine is used as a building block in the synthesis of fine chemicals, which are high-purity, specialty chemicals used in various applications, including pharmaceuticals, fragrances, and flavors. Its unique structure and reactivity make it a valuable component in the production of these high-value chemicals.

Flammability and Explosibility

Notclassified

InChI:InChI=1/C11H17NO2/c1-10-3-2-4-11(9-10)12(5-7-13)6-8-14/h2-4,9,13-14H,5-8H2,1H3

Upstream product

• 75-21-8 oxirane 
• 108-44-1 1-amino-3-methylbenzene 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 1204-57-5 N,N-bis-(2-chloro-ethyl)-m-toluidine 
• 857007-45-5 N,N-bis-(2-bromo-ethyl)-3-methyl-aniline 
• 7025-91-4 4-m-tolylmorpholine 
• 2195-55-3 2-{4-[bis-(2-hydroxy-ethyl)-amino]-2-methyl-phenylazo}-benzothiazole-6-sulfonyl fluoride 
• 51277-87-3 2,2'-(4-benzothiazol-2-ylazo-3-methyl-phenylazanediyl)-bis-ethanol 
• 101956-96-1 2,2'-(4-acenaphtho[1,2-d]thiazol-8-ylazo-3-methyl-phenylazanediyl)-bis-ethanol 
• 94960-40-4 2,2'-[3-methyl-4-(6-nitro-benzothiazol-2-ylazo)-phenylazanediyl]-bis-ethanol 
• 2193-91-1 2,2'-[3-methyl-4-(6-trifluoromethylsulfanyl-benzothiazol-2-ylazo)-phenylazanediyl]-bis-ethanol 
• 65537-86-2 2-{(2-Hydroxy-ethyl)-[3-methyl-4-(3,4,5-tris-trifluoromethyl-phenylazo)-phenyl]-amino}-ethanol 
• 103640-03-5 N,N-Bis-<β-hydroxyethyl>-3-methyl-4-nitroso-anilin 
• 1960-17-4 2,2'-[3-methyl-4-(6-trifluoromethoxy-benzothiazol-2-ylazo)-phenylazanediyl]-bis-ethanol 
• 2193-92-2 2,2'-[3-methyl-4-(6-trifluoromethanesulfinyl-benzothiazol-2-ylazo)-phenylazanediyl]-bis-ethanol 
• 80751-18-4 2-[[4-(4,6-Bis-dimethylamino-[1,3,5]triazin-2-ylazo)-3-methyl-phenyl]-(2-hydroxy-ethyl)-amino]-ethanol 
• 765299-04-5 diethyl-phosphoramidous acid 2-({2-[diethylamino-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-phosphanyloxy]-ethyl}-m-tolyl-amino)-ethyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 

Relevant academic research and scientific papers

Synthetic technology of hydroxyethylaniline ester (III)

The invention discloses a synthetic technology of hydroxyethylaniline ester (III). The synthesis process is shown by a chemical equation shown in the description. The technology has the following advantages: 1, the advantage of few instant reaction substances of a micro-channel reactor is used, so the flammable and explosive disadvantages of a hydroxyethylation reaction in a routine kettle are solved, the process safety is increased, and current chemical engineering safety operation requirements are met; and 2, the advantage of high mixing efficiency of the micro-channel reactor is used, the reaction can be carried out under solvent-free conditions when a hydroxyethylation reaction raw material is liquid, and when the excess amount of ethylene oxide is very small, so a reaction solution obtained after the hydroxyethylation reaction ends can be esterified in the micro-channel reactor, serial operation of two-step reactions is realized, and manpower and three wastes are greatly reduced. The technology is a new technology with simplified processes, and accords with environmental protection and safety requirements.

Synthesis, crystal structure and biological activity of novel diester cyclophanes

A series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, 1H nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.

Hypoxia-Selective Antitumor Agents. 3. Relationships between Structure and Cytotoxicity against Cultured Tumor Cells for Substituted N,N-Bis(2-chloroethyl)anilines

A series of aniline mustards with a wide range of electron-donating and -withdrawing substituents in the 3- and 4-positions has been synthesized and evaluated for cytotoxicity in cell culture to examine the potential of using nitro group deactivated nitrogen mustards for the design of novel hypoxia-selective anticancer drugs (Denny, W.A.; Wilson, W.R.J.Med Chem. 1986, 29, 879).Hydrolytic half-lives in tissue culture media, determined by bioassay against a cell line (UV4) defective in the repair of DNA interstrand cross-links showed the expected dependence on the Hammett electronic parameter, ?, varying from 0.13 h for the 4-amino analogue to >100 h for analogues with strongly electron-withdrawing substituents.Cytotoxic potencies in aerobic UV4 cultures showed a similar dependence on ?.This dependence predicted that the 4-nitroaniline mustard would be 7200-fold less potent than its potential six-electron reduction product, the 4-amino compound, in growth inhibition assays using a 1-h drug exposure.The measured differential was much lower (225-fold) because of the instability of the latter compound, but a differential of 17500-fold was observed in the initial rate of killing by using a clonogenic assay.The potential for formation of reactive mustards by reduction to the amine or hydroxylamine was demonstrated by the 4-nitroso compound, which had an aerobic toxicity similar to that of the amine.Although these features confirmed the original rationale, the 3-nitro- and 4-nitroaniline mustards had only minimal hypoxic selectivity against UV cells.Toxicity to hypoxic cells appears to be limited by the low reduction potentials of these compounds and consequent lack of enzymatic nitroreduction.However, this study has demonstrated that nitro groups can be used to latentiate aromatic nitrogen mustards and indicates that examples with higher reduction potentials could provide useful hypoxia-selective therapeutic agents.

Rubine disazo acid dyes for polyamides

Dyes of the formula STR1 wherein B and D are each independently 1,4-phenylene or 1,4-naphthylene; M is hydrogen, lithium, sodium, potassium or ammonium; A1 is hydrogen, C1-4 alkoxy, C1-4 alkyl, trifluoromethyl, nitro, chloro, bromo, cyano, or hydroxy; B1 and B2 are each hydrogen, C1-3 alkoxy, C1-3 alkyl, chloro or bromo; D1 is hydrogen, C1-4 alkoxy, C1-4 alkyl, or chloro; D2 is hydrogen, C1-4 alkoxy, C1-4 alkyl, chloro, bromo, fluoro, or acylamino, acyl being C1-5 alkanoyl, C1-5 alkylsulfonyl, benzoyl or benzenesulfonyl, each acyl unsubstituted or substituted with 1 to 3 of C1-2 alkyl, C1-2 alkoxy, chloro, bromo, cyano, or hydroxy; and R1 and R2 are each C1-6 alkyl, C1-6 chloro or bromoalkyl, C2-6 hydroxy- or dihydroxyalkyl, C2-6 alkoxyalkyl, C1-6 cyanoalkyl, or phenyl-C1-2 alkyl (phenyl unsubstituted or substituted with 1 to 3 of C1-2 alkyl, C1-2 alkoxy, chloro, bromo, cyano or hydroxy) are useful in dyeing natural and synthetic polyamide fibers in deep and level shades of red to blue.