910219-41-9Relevant academic research and scientific papers
Efficient synthesis of (E)-3-alkylidene-2(3H)-furanones from 3-(1-hydroxyalkyl)-2-silyloxyfurans
Boukouvalas, John,Marion, Olivier
, p. 1511 - 1514 (2006)
Several unsubstituted (E)-3-alkylmethylidene- and (E)-3-(arylmethylidene)- 2(3H)-furanones have been synthesized in highly stereoselective fashion by mesylation-elimination of 3-(1-hydoxyalkyl)-2-silyloxyfurans. The latter were prepared from 2-tri-isopropylsilyloxy-3-bromofuran by halogen-lithium exchange and reaction of the in situ generated 3-lithiated silyloxyfuran with aldehydes. Georg Thieme Verlag Stuttgart.
