91047-74-4Relevant academic research and scientific papers
C-F bond cleavage enabled redox-neutral [4+1] annulation via C-H bond activation
Wang, Cheng-Qiang,Ye, Lu,Feng, Chao,Loh, Teck-Peng
supporting information, p. 1762 - 1765 (2017/02/15)
Using α,α-difluoromethylene alkyne as a nontraditional one-carbon reaction partner, a synthetically novel method for the construction of isoindolin-1-one derivatives via Rh(III)-catalyzed [4+1] annulation reaction is reported. The 2-fold C-F bond cleavage not only enables the generation of desired product under an overall oxidant-free condition but also results in a net migration of carbon-carbon triple bond. In addition, the present reaction protocol exhibits a tolerance of a wide spectrum of functional groups due to the mild reaction conditions employed.
CDK INHIBITORS
-
Page/Page column 71, (2010/07/09)
The present invention relates to CDK inhibitors and their use in the treatment of cell proliferative diseases such as cancer.
CDK INHIBITORS CONTAINING A ZINC BINDING MOIETY
-
Page/Page column 66; 67, (2009/04/25)
The present invention relates to CDK inhibitors and their use in the treatment of cell proliferative diseases such as cancer. The compounds of the invention may further act as HDAC inhibitors.
4-halogenostilbene derivatives and processes for their preparation
-
, (2008/06/13)
Novel compounds of the formula STR1 and processes for their preparation are described. X represents bromine or iodine and R1, R2 and R3 have the meaning indicated in the patent claim. The compounds (I) are valuable intermediates for the preparation of fluorescent brighteners of the divinylstilbene type.
SELECTIVE PREPARATION OF NON-SYMMETRICALLY SUBSTITUTED DIVINYLBENZENES BY PALLADIUM-CATALYSED ARYLATIONS OF ALKENES WITH BROMOBENZOIC ACID DERIVATIVES
Spencer, Alwyn
, p. 323 - 332 (2007/10/02)
Palladium-catalysed arylation of alkenes with the three bromobenzoic acids or their acyl chlorides provides an efficient and selective method for the preparation of non-symmetrically substituted divinylbenzene derivatives.In the presence of palladium acet
