91049-45-5

Basic information

• Product Name: 4-methylpentane-1,2-diol
• CAS NO: 91049-45-5
• Molecular Weight: 118.176
• Mol File: 91049-45-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4-methylpentane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylpentane-1,2-diol(91049-45-5)
• EPA Substance Registry System: 4-methylpentane-1,2-diol(91049-45-5)

Safety Data

• Hazardous Substances Data: 91049-45-5(Hazardous Substances Data)

Upstream product

• 926-56-7 4-methyl-1,3-pentadiene 
• 691-37-2 4-Methyl-1-pentene 
• 173917-47-0 1-benzyloxy-4-methylpentan-2-ol 
• 125990-20-7 phyllofoliaspongin 
• 103273-35-4 4-methyl-pent-3-ene-1,2-diol 
• 103260-84-0 4,5-diacetoxy-2-methyl-pent-2-ene 
• 158393-61-4 2-Diazo-4-methyl-pentanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 

Downstream Products

• 23850-78-4 4-methyl-1,2-epoxypentane 
• 24347-54-4 (S)-(-)-4-methyl-1,2-pentanediol 
• 111221-87-5 2-hydroxy-4-methylpentyl-p-toluenesulfonate 

Relevant articles and documents

Cyclodehydration and Chlorination of Simple Diols with Triphenylphosphine and tert-Butyl Hypochlorite

The reagent triphenylphosphine-tert-butyl hypochlorite converts 1,4-diols into the corresponding tetrahydrofurans and 1,2-diols into a mixture of the regioisomeric chlorohydrins and the epoxides at -78 deg C followed by warming to ambient temperature (ca. 30 deg C).Symmetrical diols give largely chlorohydrins and dichlorides.

Osmium tetroxide in poly(ethylene glycol) (PEG): A recyclable reaction medium for rapid asymmetric dihydroxylation under Sharpless conditions

PEG (400) has been used as a recyclable and rapid reaction medium for the asymmetric dihydroxylation of olefins; Sharpless ligand is efficiently recovered and recycled with good enantioselectivity.

Preparation of optically active α-Silylcarbonyl compounds using asymmetric alkylation of α-Silylacetic esters and asymmetric metal-carbene insertion into the Si-H bond.

Substituted α-silylacetic esters have been prepared in good yields and with reasonable diastereoselectivities by three different routes. The first two involved alkylation of the parent α-silylacetic ester enolates, with the chiral auxiliaries being present either on silicon or on the ester function. The third route involving asymmetric insertion of metal-carbenoids into the Si-H band was found to afford better diastereoselectivities, using pantolactane as chiral auxiliary.