910537-64-3Relevant academic research and scientific papers
Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III)
Carrion, M. Dora,Lopez Cara, Luisa C.,Camacho, M. Encarnacion,Tapias, Victor,Escames, Germaine,Acuna-Castroviejo, Dario,Espinosa, Antonio,Gallo, Miguel A.,Entrena, Antonio
, p. 2579 - 2591 (2008/12/23)
We have previously described a series of 4,5-dihydro-1H-pyrazole as moderately potent nNOS inhibitors. As a follow up of these studies, we report here the preparation and the preliminary evaluation of a series of 1-alkyl-3-benzoyl-4,5-dihydro-1H-pyrazole
An unexpected aromatization during the N-alkylation reaction of 3,4-dihydro-1H-pyrazole derivatives: insight into the reaction mechanism
López-Cara, Luisa C.,Encarnación Camacho,Carrión, María D.,Gallo, Miguel A.,Espinosa, Antonio,Entrena, Antonio
, p. 6239 - 6242 (2007/10/03)
In this letter we describe the unexpected aromatization that takes place during the N-alkylation reaction performed on several 3-(2-nitrobenzoyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl esters, giving rise to a mixture of 1-alkyl-3-(2-nitrobenzoy
