910537-65-4Relevant academic research and scientific papers
An unexpected aromatization during the N-alkylation reaction of 3,4-dihydro-1H-pyrazole derivatives: insight into the reaction mechanism
López-Cara, Luisa C.,Encarnación Camacho,Carrión, María D.,Gallo, Miguel A.,Espinosa, Antonio,Entrena, Antonio
, p. 6239 - 6242 (2006)
In this letter we describe the unexpected aromatization that takes place during the N-alkylation reaction performed on several 3-(2-nitrobenzoyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid methyl esters, giving rise to a mixture of 1-alkyl-3-(2-nitrobenzoy
Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III)
Carrion, M. Dora,Lopez Cara, Luisa C.,Camacho, M. Encarnacion,Tapias, Victor,Escames, Germaine,Acuna-Castroviejo, Dario,Espinosa, Antonio,Gallo, Miguel A.,Entrena, Antonio
, p. 2579 - 2591 (2008/12/23)
We have previously described a series of 4,5-dihydro-1H-pyrazole as moderately potent nNOS inhibitors. As a follow up of these studies, we report here the preparation and the preliminary evaluation of a series of 1-alkyl-3-benzoyl-4,5-dihydro-1H-pyrazole
