910579-13-4Relevant academic research and scientific papers
Chelated ester enolates as versatile nucleophiles for direct nucleophilic attack on aromatic nitro groups
Stolz, Daniel,Pick, Rigobert,Kazmaier, Uli
, p. 1616 - 1618 (2006)
Chelated amino acid ester enolates react with aromatic nitro compounds at the nitrogen atom. Best results were obtained with TFA-protected glycinates. Georg Thieme Verlag Stuttgart.
Aromatic nitro groups and their reactions with chelated ester enolates
Stolz, Daniel,Kazmaier, Uli,Pick, Rigobert
, p. 3341 - 3347 (2008/09/17)
Chelated amino acid ester enolates react with aromatic nitro compounds in a 1,3-addition mode at the nitro group giving amino acids bearing an aryl(hydroxy)amino side chain. Best results were obtained with trifluoroacetyl-protected glycinates. Two equivalents of enolate are necessary for complete conversion, because one equivalent is oxidized during the reaction. Georg Thieme Verlag Stuttgart.
