910649-07-9Relevant academic research and scientific papers
Palladium-catalyzed C-C coupling: efficient preparation of new 5-thio-β-d-xylopyranosides as oral venous antithrombotic drugs
Bondoux,Mignon,Ou,Renaut,Thomas,Barberousse
scheme or table, p. 3872 - 3876 (2009/09/30)
First examples of a Suzuki and Stille cross-coupling reaction to prepare derivatives of pyridinyl 5-thio-β-d-xylopyranosides are described. Some of these compounds are orally active in an animal model of venous thrombosis.
Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics
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, (2009/01/20)
The invention relates to novel 5-thioxylose compounds, preferably derivatives of the 5-thioxylopyranose type, to the process for their preparation and to their use as active principles of drugs intended especially for the treatment or prevention of thrombosis or cardiac insufficiency.
