910654-28-3

Upstream product

• 822-36-6 4-methyl-1H-imidazole 
• 400-74-8 2-Fluoro-5-nitrobenzotrifluoride 

Downstream Products

• 641570-89-0 4-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)aniline 
• 1542265-57-5 3-iodo-4-methyl-N-(4-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide 

Relevant academic research and scientific papers

Protein Kinase Inhibitors

The present invention relates to compounds of Formula I: as well as pharmaceutically acceptable salts, hydrates, isomers, or solvates thereof, wherein the variables are described herein. The present invention further relates to pharmaceutical compositions which comprise the compounds of Formula I, and to methods for inhibiting protein kinase and methods of treating diseases, such as cancers, inflammation.

Biaryl derived amide modulators of vanilloid VR1 receptor

The invention is directed to novel vanilloid receptor type 1 (VR1) ligands. More specifically, the invention relates to novel biaryl-derived amides that are potent antagonists or agonists of VR1. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.