910658-45-6Relevant articles and documents
The 1H NMR method for the determination of the absolute configuration of 1,2,3-prim,sec,sec-triols
Lallana, Enrique,Freire, Felix,Seco, Jose Manuel,Quinoa, Emilio,Riguera, Ricardo
, p. 4449 - 4452 (2006)
The absolute configuration of 1,2,3-prim,sec,sec-triols can be assigned by comparison of the 1H NMR spectra of the tris-(R)- and the tris-(S)-MPA ester derivatives. An experimental demonstration of this correlation with 24 triols of known absolute configuration and a protocol using two parameters-ΔδRS(H3) and the difference between ΔδRS(H2) and ΔδRS(H3) = |Δ(ΔδRS)|-for its application to the determination of the absolute configuration of other triols are presented.