910808-85-4Relevant academic research and scientific papers
Preparation of 7-halo-indoles by thallation of N-formylindoline and their attempted use for synthesis of the right-hand segment of chloropeptin
Yamada, Yaeko,Arima, Shiho,Okada, Chiharu,Akiba, Ai,Kai, Toshitsugu,Harigaya, Yoshihiro
, p. 788 - 794 (2006)
7-Substituted (Cl, Br, I) indoles were synthesized by using thallation of N-formylindoline as a key reaction. Two precursor tripeptides for the right-hand segment of chloropeptin were synthesized by using (R)-7′-iodo and 7′-bromotryptophans derived from each 7-substituted indole (I, Br) obtained by the above procedure.
