91088-55-0

Usage

Uses

Used in Industrial Health Monitoring:
N-ACETYL-S-(4-NITROPHENYL)-L-CYSTEINE is used as a biomarker for low levels of exposure to benzene in industry. This allows for the detection and monitoring of benzene exposure, which is crucial for ensuring the health and safety of workers in various industrial sectors.

InChI:InChI=1/C11H12N2O5S/c1-7(14)12-10(11(15)16)6-19-9-4-2-8(3-5-9)13(17)18/h2-5,10H,6H2,1H3,(H,12,14)(H,15,16)/t10-/m0/s1

Upstream product

• 616-91-1 N-acetylcystein 
• 24067-17-2 4-nitrophenylboronic acid 
• 5429-56-1 N-Acetamidoacrylic acid 
• 1849-36-1 para-nitrobenzenethiol 
• 701-57-5 1-methylthio-4-nitro-benzene 
• 52-90-4 L-Cysteine 

Downstream Products

• 93001-14-0 N-Acetyl-3-(4-nitro-phenylmercapto)-L-alanin-methylester 
• 5449-06-9 S-(4-nitro-phenyl)-cysteine 

Relevant academic research and scientific papers

Boronic Acid Pairs for Sequential Bioconjugation

Boronic acids can play diverse roles when applied in biological environments, and employing boronic acid structures in tandem could provide new tools for multifunctional probes. This Letter describes a pair of boronic acid functional groups, 2-nitro-arylboronic acid (NAB) and (E)-alkenylboronic acid (EAB), that enable sequential cross-coupling through stepwise nickel- and copper-catalyzed processes. The selective coupling of NAB groups enables the preparation of stapled peptides, protein-protein conjugates, and other bioconjugates.

Transition-Metal-Free Aryl-Heteroatom Bond Formation via C-S Bond Cleavage

Aryl-heteroatom bonds (C-Het) are almost ubiquitously present in chemical molecules. However, methods for diverse C-Het bond formations from a simple substrate are limited. Herein, we report a convenient and efficient C-S bond transformation of aryl sulfoniums to various C-Het bonds (C-O, C-S, C-Sn, C-Si, C-Se) in the absence of any transition-metal catalyst. These reactions proceeded in mild conditions with a wide substrate scope.