91089-33-7Relevant articles and documents
Synthesis of linearly and angularly fused indane-based constrained α-amino acid derivatives
Kotha, Sambasivarao,Krishna, Nimita Gopal,Misra, Shilpi,Khedkar, Priti
, p. 2945 - 2950 (2011)
The benzocyclobutene-based α-amino acid derivative, ethyl 5-acetamido-2,4,5,6-tetrahydro-1H-cyclobuta[f]indene-5-carboxylate is synthesized via coupling of a benzocyclobutene-derived dibromide with ethyl isocyanoacetate as the key step, followed by hydrolysis and subsequent acetylation. This methodology is generalized in order to prepare various linearly and angularly fused indane-based α-amino acid derivatives. Georg Thieme Verlag Stuttgart - New York.