91100-74-2Relevant articles and documents
NAD(P)H and Acetyl-CoA Models: Part I - Reaction of Nitrosobenzene with 1,1'-Diacetyl-1,1',4,4'-tetrahydro-4,4'-bipyridine
Juneja, T. R.,Ojha, Anil,Gupta, R. L.
, p. 60 - 66 (2007/10/02)
In vivo metabolic conditions of coenzymes NAD(P)H and acetyl-CoA may be simulated in 1,1'-diacetyl-1,1',4,4'-tetrahydro-4,4'-bipyridine (DTB) loosing hydride ion with concomitant loss of acetyl cation.This is illustrated by the formation of almost same products on treatment of nitrosobenzene with DTB as formed in vivo.The simultaneous loss of hydride and acetyl cation by DTB converts nitrosobenzene to activated labile intermediate O-acetylphenylhydroxylamine (12) which has been considered responsible for the origin of majority of products.