911209-02-4Relevant academic research and scientific papers
A study on the synthesis of calix[4 and 6]arenes using alternately arranged phloroglucinols and p-tert-butylphenols
Sato, Shingo,Yashiro, Akihito,Tsushima, Naoki,Hosaka, Kenta
scheme or table, p. 1173 - 1176 (2009/09/06)
A method for the synthesis of calix[4 and 6]arenes with two or three alternately arranged phloroglucinols and p-tert-butylphenols was studied using 3+1 and 5+1 approaches, compared to a simple one-pot synthesis based on a 1+1 approach. By using Yb(OTf)3 as a catalyst, each calix[4 and 6]arenes was afforded, in an overall yield of 20.7% and 11.8% in the 3+1 and 5+1 approaches, respectively, and 24.6% and 19.9% using a 1+1 approach with chlorobenzene and toluene as refluxing solvents, respectively.
