2203-14-7

Usage

Uses

Used in Electronics Industry:
1,3-Benzenedimethanol, 5-(1,1-dimethylethyl)-2-hydroxyis used as a precursor for photosensitive resin compositions containing polyimide. Its application in this context is due to its ability to form stable and heat-resistant materials, which are essential for the production of electroluminescent elements.
Used in Chemical Industry:
As a polybenzoxazole precursor, 1,3-Benzenedimethanol, 5-(1,1-dimethylethyl)-2-hydroxyplays a crucial role in the development of advanced materials with high thermal stability and mechanical strength. These properties make it an ideal candidate for use in the chemical industry, where such materials are in high demand for various applications.

InChI:InChI=1/C12H18O3/c1-12(2,3)10-4-8(6-13)11(15)9(5-10)7-14/h4-5,13-15H,6-7H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 98-54-4 para-tert-butylphenol 
• 56-23-5 tetrachloromethane 
• 7732-18-5 water 

Downstream Products

• 123886-22-6 2,6-Bis-(3-allophanoyl-acryloyloxymethyl)-4-tert-butyl-phenol 
• 72109-62-7 2-<5-tert-butylsalicyl-3-(5-methylsalicyl)>-4-methylphenol 
• 810-52-6 4-(tert-butyl)-2,6-bis{[5-(tert-butyl)-2-hydroxyphenyl]methyl}phenol 
• 1264-81-9 4-(tert-butyl)-2,6-bis{{5-(tert-butyl)-3-{{5-(tert-butyl)-3-{[5-(tert-butyl)-2-hydroxyphenyl]methyl}-2-hydroxyphenyl}methyl}-2-hydroxyphenyl}methyl}phenol 
• 1264-58-0 4-(tert-butyl)-2,6-bis{{5-(tert-butyl)-3-{[5-(tert-butyl)-2-hydroxyphenyl]methyl}-2-hydroxyphenyl}methyl}phenol 
• 1666-01-9 3-methyl-5-tert-butyl-2-hydroxybenzaldehyde 
• 84501-28-0 2-hydroxy-5-t-butylisophthalaldehyde 
• 10339-95-4 4-(tert-butyl)-2,6-bis(chloromethyl)phenol 
• 5011-36-9 2, 6-bis(bromomethyl)-4-^tbutylphenol 
• 94516-52-6 5-tert-butyl-1,3-bis-hydroxymethyl-2-(toluene-4-sulfonyloxy)-benzene 
• 66824-29-1 2,6-bis(3,5-dimethyl-2-hydroxybenzyl)-4-t-butylphenol 
• 127679-79-2 4-tert-Butyl-2,6-bis<(5-chloro-2-hydroxyphenyl)methyl>phenol 
• 145020-78-6 3,7,11-tribenzyl-15,55,95-tri-tert-butyl-3,7,11-triaza-1,5,9(1,3)-tribenzenacyclododecaphane-12,52,92-triol 
• 206879-62-1 (5-tert-Butyl-3-hydroxymethyl-2-methoxymethoxy-phenyl)-methanol 

Relevant academic research and scientific papers

Structure, thermal stability, antioxidant activity and DFT studies of trisphenols and related phenols

Two kinds of trisphenols have been successfully synthesized and their structures were confirmed by IR spectra, 1HNMR, 13CNMR, mass spectra and X-ray diffraction. They exhibited better thermal stability than both monophenol and bisphenols due to their higher molecular weight. Moreover, their antioxidant activities have been investigated in lubricant oil using PDSC and RBOT. The results showed that the o-trisphenol 3b exhibited the best antioxidant activity while the p-trisphenol 3a was the worst. In addition, their relationship between structures and properties has been further explored by a series of DFT calculations including the BDE values, the IP values and the Gibbs free energy barriers for the reaction between phenols and methylperoxyl radicals.

A novel calixsalen macrocycle: Metal sensing behavior for Zn2+ and intracellular imaging application

The chiral [3+3] macrocycle 1 which displays a calixarene-like crystal structure has been synthesized. The UV/Vis and fluorescence spectral studies show that 1 and Zn2+ have a 1:3 complex stoichiometry. It exhibits high selectivity toward Znsu

Two are better than one - Synthesis of novel blue and green emissive hydroxy-oxadiazoles

We describe herein synthesis of novel hydroxy-bis-2,5-disubstituted-1,3,4-oxadiazoles and their ability to emit green light, through ESIPT mechanism. Unlike previous reports, our compounds exhibit very good quantum yields, most likely avoiding the presume

CALIXARENE COMPOUNDS AND USES THEREOF

Compounds of general Formula (I) wherein the elements A, L, R1 and R2 have a defined meaning, and their medical and non-medical use.

Process preparation method of 4-substituted-2, 6-dimethylphenol

The present invention discloses a process preparation method of 4-substituted-2, 6-dimethyl phenol. According to the process preparation method, a preparation route method is improved and optimized, reaction conditions are optimized, post-treatment and purification methods are improved, so that the danger grade of operation and the production cost are reduced; and the requirement for the corrosionresistance grade of reaction container equipment is low, the operation is safe, and the post-treatment is environment-friendly; and the prepared 4-substituted-2, 6-dimethyl phenol has less impurities, thus, the purity and the quality of an intermediate product are greatly improved while the yield is improved as well, the difficulty of process control in the production process of a subsequent rawmaterial medicine product is improved, and the quality and qualification rate of the subsequent raw material medicine product are improved; and the steps of the preparation method is simple to operate, the solvent and the process conditions are safe and easy to achieve, environment-friendly production is achieved, and the preparation method has wide application prospect.

Homodinuclear [Fe(III)?Fe(III)] and [Zn(II)?Zn(II)] complexes of a binucleating [N4O3] symmetrical ligand with purple acid phosphatase (PAP) and zinc phosphoesterase like activity

The homodinuclear [Fe(III)–Fe(III)] (2) and [Zn(II)–Zn(II)] (3) complexes of binucleating [N4O3] symmetrical ligand (1) of the formulation, H3L (L = 2,6-bis{[(2-hydroxybenzyl)(2-pyridylmethyl)amino]methyl}-4-t-butylphenolate), display purple acid phosphatase (PAP) and zinc phosphoesterase like activity. For the two complexes, the spectrophotometric titration and the ESI-MS studies supported the existence of an equilibrium between a triaquated species, {L[(H2O)FeIII(μ-H2O)FeIII(H2O)]}3+ (2A) and {L[(H2O)ZnII(μ-H2O)ZnII(H2O)]}+ (3A), a diaquated and monohydroxo species, {L[(H2O)FeIII(μ-H2O)FeIII(OH)]}2+ (2B) and {L[(H2O)ZnII(μ-H2O)ZnII(OH)]} (3B), a monoaquated and dihydroxo species, {L[(H2O)FeIII(μ-OH)FeIII(OH)]}+ (2C) and {L[(H2O)ZnII(μ-OH)ZnII(OH)]}? (3C), and a trihydroxo species, {L[(HO)FeIII(μ-OH)FeIII(OH)]} (2D) and {L[(HO)ZnII(μ-OH)ZnII(OH)]}2? (3D), depending upon the pH of the solution. Of these, the active species namely, a monoaquated and dihydroxo species, {L[(H2O)FeIII(μ-OH)FeIII(OH)]}+ (2C) and {L[(H2O)ZnII(μ-OH)ZnII(OH)]}? (3C), hydrolyzed an activated substrate bis(2,4-dinitrophenyl)phosphate at the pH range of 5.5–10.5, displaying Michealis–Menton kinetics. Significantly enough, the catalyst-substrate adduct of the type {L[FeIII(μ-OH)(μ-RPO4)FeIII]} (2F) has been detected by ESI-MS for the dinuclear [Fe(III)–Fe(III)] complex (2).

Water-promoted ortho-selective monohydroxymethylation of phenols in the NaBO2 system

Water-promoted ortho-selective monohydroxymethylation of phenols in the NaBO2 system generates salicyl alcohols in 65-97% yields. A remarkable rate-enhancement by water was observed, and NaBO2 appeared to serve the dual role of a suitable base and an efficient chelating reagent. This protocol possesses many advantages such as short reaction times, expanded substrate scope, and high mono- and regio-selectivities. The experimental results were explained by the calculations based on local ionisation energy minima, leading to a possible reaction mechanism.

Distinct structures of inorganic-organic supramolecular assemblies based on discrete metallocyclic complexes incorporating flexible imidazole ligands: Syntheses, crystal structures and properties

Three new interesting discrete dinuclear metallocyclic complexes, namely, {[Pd2(1)4](NO3)4· 2DMSO· 2H2O}n (4), [Pd2(2) 2Br4]n (5), and {[Pd2(3) 2Cl4]·4DMSO}n (6) have been successfully synthesized by the reaction of flexible exo-bidentate imidazole-containing ligands 1, 3-bis(imidazol-1-ylmethyl)benzene (1), 1, 3-bis(imidazol-1-ylmethyl)- 5-methylbenzene (2), and 2, 6-bis(imidazol-1-ylmethyl)-4-tert-butyl-phenol (3) with corresponding palladium salts. All these complexes were characterized by NMR spectroscopy in combination with elemental analysis, powder X-ray diffraction (PXRD), single-crystal X-ray diffraction, and thermal gravimetric analysis (TGA), respectively. Though all three complexes involve the similar supramolecular building blocks [2+2] metallocyclic units, under the inducement effect of the organic ligands, compounds 4-6 exhibit delicate geometric diversification of the resulting high-dimensional inorganic-organic supramolecular assemblies (e.g., [4+2] lantern-like cage structure, 1D channel, and 2D undulating framework, respectively). Furthermore, these results demonstrate that the secondary interactions such as intermolecular π ··· π stacking interactions and hydrogen bonds could play important roles in the aspect of linking low-dimensional entities into high-dimensional supramolecular frameworks.

Lower rim 1,3-diderivative of calix[4]arene-appended salicylidene imine (H2L): Experimental and computational studies of the selective recognition of H2L toward Zn2+ and sensing phosphate and amino acid by [ZnL]

A new 1,3-diderivative of calix[4]arene appended with hydroxymethyl salicylyl imine has been synthesized and its ion recognition toward biologically relevant Mn+ ions studied. The receptor H2L showed selectivity toward Zn2+/sup

Self-assembly from metal-organic vesicles to globular networks: Metallogel-mediated phenylation of indole with phenyl boronic acid

Self-assembly of the conformationally flexible bismethylimidazolyl ligands with Pd(OAc)2 is described. Depending on whether the ligands provide the hydrogen bonding donor, a switching of metal-organic vesicles to globular networks gelating solvents is achieved. The metallogels exhibit catalytic activity for the cross-coupling of indole with phenyl boronic acid.