911210-40-7

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 257928-45-3 4-(4-benzyloxyphenyl)-1-(1-phenylethyl)-1,2,3,4-tetrahydro-pyridin-3-ol 
• 911210-41-8 4-(4-Benzyloxyphenyl)-1-(1-phenylethyl)-3-triisopropylsilanyloxy-1,2,3,4-tetrahydro-pyridine 

Downstream Products

• 911210-39-4 4-(4-hydroxyphenyl)-5-triisopropylsilanyloxypiperidin-3-ol 
• 911210-38-3 benzyl 3-hydroxy-4-(4-hydroxyphenyl)-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-37-2 benzyl 4-(4-allyloxyphenyl)-3-hydroxy-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-32-7 benzyl 3-hydroxy-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-(4-phenoxyphenyl)piperidine-1-carboxylate 
• 911210-34-9 (3R,4R,5S)-4-(4-hydroxy-phenyl)-3-[4-(3-methoxy-propyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 
• 911210-35-0 (3R,4R,5S)-4-(4-hydroxy-phenyl)-3-[4-(3-methoxy-propyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 
• 911210-33-8 benzyl 3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-(4-phenoxy-phenyl)-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-58-7 benzyl 3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-[4-(pyridin-2-yloxy)phenyl]-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-36-1 (3R,4R,5S)-4-(4-allyloxy-phenyl)-3-[4-(3-methoxy-propyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS

Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, W, X, Z and n as stated in Claim 1 have renin-inhibiting properties and can be used as medicines.

ORGANIC COMPOUNDS

The application relates to novel substituted piperidines of the general formula (I) in which R1, R2, R3, R4, W, X, Z, m and n are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.