257928-45-3

Basic information

• Product Name: 3-Pyridinol, 1,2,3,6-tetrahydro-1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-, (3S)-
• CAS NO: 257928-45-3
• Molecular Formula: C26H27NO2
• Molecular Weight: 559.864
• Mol File: 257928-45-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Pyridinol, 1,2,3,6-tetrahydro-1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinol, 1,2,3,6-tetrahydro-1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-, (3S)-(257928-45-3)
• EPA Substance Registry System: 3-Pyridinol, 1,2,3,6-tetrahydro-1-[(1R)-1-phenylethyl]-4-[4-(phenylmethoxy)phenyl]-, (3S)-(257928-45-3)

Safety Data

• Hazardous Substances Data: 257928-45-3(Hazardous Substances Data)

Upstream product

• 911210-41-8 4-(4-Benzyloxyphenyl)-1-(1-phenylethyl)-3-triisopropylsilanyloxy-1,2,3,4-tetrahydro-pyridine 
• 144-55-8 sodium hydrogencarbonate 
• 257928-40-8 (1R,6R)-6-(4-benzyloxy-phenyl)-3-[(R)-1-phenyl-ethyl]-7-oxa-3-aza-bicyclo [4.1.0] heptane 
• 257928-43-1 (R)-4-(4-benzyloxy-phenyl)-1-(1-phenyl-ethyl)-1,2,3,6-tetrahydro-pyridine 

Downstream Products

• 911855-75-9 (S)-4-(4-Benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-3-triisopropylsilanyloxy-1,2,3,6-tetrahydro-pyridine 
• 303043-17-6 (3R,4R,5S)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-4-(4-hydroxy-phenyl)-piperidin-3-ol 
• 303043-18-7 (3S,4R,5R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-5-hydroxy-4-(4-hydroxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 303043-16-5 (3R,4R,5S)-4-(4-Benzyloxy-phenyl)-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-1-((R)-1-phenyl-ethyl)-piperidin-3-ol 
• 303043-19-8 (3S,4R,5R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-5-hydroxy-4-{4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 303043-22-3 (R)-3-[(3S,4R,5R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-5-(4-methoxy-naphthalen-2-ylmethoxy)-piperidin-3-yloxy]-propane-1,2-diol 
• 303043-26-7 (3R,4R,5S)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-(4-methoxy-naphthalen-2-ylmethoxy)-5-[(2R)-oxiranylmethoxy]-piperidine-1-carboxylic acid tert-butyl ester 
• 303043-27-8 (3S,4R,5R)-3-[(2R)-2-hydroxy-3-methoxy-propoxy]-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-5-(4-methoxy-naphthalen-2-ylmethoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 303043-21-2 (3S,4R,5R)-3-[(4S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy]-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-5-(4-methoxy-naphthalen-2-ylmethoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 303043-23-4 (3S,4R,5R)-3-((R)-2,3-Dihydroxy-propoxy)-4-{4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl}-5-(4-methoxy-naphthalen-2-ylmethoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 911210-36-1 (3R,4R,5S)-4-(4-allyloxy-phenyl)-3-[4-(3-methoxy-propyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 
• 911210-58-7 benzyl 3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-[4-(pyridin-2-yloxy)phenyl]-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-33-8 benzyl 3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-(4-phenoxy-phenyl)-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 911210-35-0 (3R,4R,5S)-4-(4-hydroxy-phenyl)-3-[4-(3-methoxy-propyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Substituted Piperidines as Renin Inhibitors

Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines.

Process and intermediates for preparation of substituted piperidine-epoxides

The present invention concerns intermediates useful in and a process for the preparation of a compound of formula 1 or a salt thereof comprisingepoxidation of a compound of formula 2 or a salt thereof wherein A, R1and R2are as herein