911286-07-2

Upstream product

• 321569-81-7 2',4'-bis(benzyloxy)-3'-iodo-6'-(methoxymethoxy)acetophenone 
• 321569-79-3 2',4'-dihydroxy-3'-iodo-6'-(methoxymethoxy)acetophenone 
• 67052-53-3 4',6'-bis(benzyloxy)-2'-(methoxymethoxy)acetophenone 
• 71386-98-6 2',4'-dihydroxy-6'-(methoxymethoxy)acetophenone 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 911286-02-7 1-[6-benzoyloxy-2,4-bis(benzyloxy)-3-iodophenyl]-2-(3,4-methylenedioxyphenyl)-3,3-dimethoxypropan-1-one 
• 911286-04-9 5,7-bis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)-3',4'-methylenedioxyisoflavone 
• 911286-05-0 7-benzoyloxy-5-hydroxy-6-(3-hydroxy-3-methylbutyl)-3',4'-methylenedioxyisoflavone 
• 911286-03-8 5,7-bis(benzyloxy)-6-iodo-3',4'-methylenedioxyisoflavone 
• 911285-98-8 5,7-dihydroxy-6-(3-hydroxy-3-methylbutyl)-3',4'-methylenedioxyisoflavone 
• 911286-06-1 7-benzoyloxy-6-(3-hydroxy-3-methylbutyl)-3',4'-methylenedioxy-5-tosyloxyisoflavone 

Downstream Products

• 22044-58-2 Derrubone 
• 911412-08-3 7-benzoyloxy-5-hydroxy-6-(3-methyl-2-butenyl)-3',4'-methylenedioxyisoflavone 

Relevant academic research and scientific papers

Microwave-assisted regioselective synthesis of natural 6-prenylpolyhydroxyisoflavones and their hydrates with hypervalent iodine reagents

Microwave-assisted oxidative rearrangement of 3′-iodotetraalkoxychalcones with hypervalent iodine such as [hydroxy(tosyloxy)iodo]benzene or [bis(trifluoroacetoxy)iodo]benzene, followed by microwave-mediated hydrolysis and in situ cyclization of the resultant acetals gave 6-iodotrialkoxyisoflavones. Pd(0)-catalyzed coupling reaction of the 6-iodoisoflavones with 2-methyl-3-butyn-2-ol under microwave irradiation gave 6-alkynylisoflavones, whose hydrogenation gave the respective hydrates of wighteone, lupisoflavone and derrubone. Wighteone (1a), lupisoflavone (1b) and derrubone (1c) were obtained by dehydration of their respective hydrates under microwave irradiation.