91131-10-1Relevant articles and documents
Benzo[c]quinolizin-3-ones: A novel class of potent and selective nonsteroidal inhibitors of human steroid 5α-reductase 1
Guarna,Machetti,Occhiato,Scarpi,Comerci, Alessandra,Danza, Giovanna,Mancina, Rosa,Serio, Mario,Hardy, Kimber
, p. 3718 - 3735 (2007/10/03)
The synthesis and biological evaluation of a series of novel, selective inhibitors of isoenzyme 1 of human 5α-reductase (5αR) (EC 1.3.99.5) are reported. The inhibitors are 4aH- (19-29) or 1H-tetrahydrobenzo[c]quinolizin-3-ones (35-47) bearing at position