1951-11-7

Upstream product

• 141-75-3 butyryl chloride 
• 625-68-3 3-chlorobutyric acid 
• 201230-82-2 carbon monoxide 
• 75-19-4 cyclopropane 
• 71-43-2 benzene 
• 56-23-5 tetrachloromethane 
• 7791-25-5 sulfuryl dichloride 
• 94-36-0 dibenzoyl peroxide 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 871882-79-0 3-chloro-1-(2-hydroxy-5-methyl-phenyl)-butan-1-one 
• 91131-10-1 3-chloro-butyric acid p-toluidide 
• 307335-67-7 3-chloro-butyric acid-(4-chloro-anilide) 
• 90869-59-3 3-chloro-butyric acid anilide 
• 859809-74-8 3-chloro-butyric acid o-toluidide 
• 37795-72-5 2-methyl-2,3-dihydro-isoxazolo[3,2-b]quinazolin-9-one 
• 6464-10-4 3-Chlor-4-(3-chlor-butyryl)-phenoxyessigsaeure 
• 6270-75-3 2-Propenyl-benzthiazol 
• 82458-47-7 (3-chlorobutyryl)diphenylphosphane 
• 85221-85-8 3-Chloro-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-butyramide 
• 1263176-53-9 4-(2-(2-chloropropyl)-5-(2,4-dichlorophenyl)-4,6-dioxo-3,4,6,7,8,9-hexahydropyrimido[4,5-b]quinolin-10(5H)-yl)benzenesulfonamide 
• 1263176-46-0 3-chloro-N-(3-cyano-4-(2,4-dichlorophenyl)-5-oxo-1-(4-sulfamoylphenyl)-1,4,5,6,7,8-hexahydroquinolin-2-yl)butanamide 
• 34880-85-8 3-chloro-1-phenylbutan-1-one 
• 70336-24-2 3-chloro-1-(4-fluorophenyl)butan-1-one 

Relevant academic research and scientific papers

Chlorocarbonylation of Unsaturated Substrates Catalysed by Palladium Complexes in the Presence of Anhydrous HCl

Chloroacyl halides are obtained under mild conditions by catalytic carbonylation of allylic halides or ethene and allyl chloride under CO and anhydrous HCl pressure; excellent selectivities for formation of dichloroacyl and chloroacyl derivatives are achi

AN IMPROVED SYNTHESIS OF HEXAMETHYLPHENALENE

The synthesis of 1,3,4,6,7,9-hexamethylphenalene (2) has been improved from 15 steps to a four step procedure.The overall yield has been increased from an estimated 5percent to 45percent.Key steps in the synthesis are the reaction of 3,5-dimethylbenzylmagnesium chloride with 2,4-pentanedioato lithium in THF to make 5-(3,5-dimethylphenyl)-4-methyl-4-hydroxy-2-pentanone (5) and the Lewis acid acylation-alkation of 1,3,6,8-tetramethylnaphthalene using 3-chlorobutanoic chloride in hexane with sonicaton to make 1,3,4,6,7,9-hexamethyl-phenalane (2).

Chlorination of Butyryl Chloride in the Liquid Phase

The photochlorination of butyryl chloride in the liquid phase at room temperature has been studied.The progress of the chlorination was followed, the mono- and dichloro products being identified and estimated by GLC as their methyl esters.The isomer distribution has been studied in detail at different stages of chlorination.The main compounds identified in the reaction mixture were substrate until 0.5 h, 3-chlorobutyryl chloride between 0.5 and 2.5 h, 3,4-dichlorobutyryl chloride between 2.5 and 7.5 h, 3,3-dichlorobutyryl chloride between 7.5 and 10.0 h and 4,4-dichlorobutyryl chloride after chlorination for 10.0 h.Polychloro compounds were, however, the main products towards the end of the process.

Interaction of Cyclopropane with Platinum-Metal Chlorides under Carbon Monoxide Pressure in Benzene

The six platinum-metal chlorides were reacted with cyclopropane in benzene under carbon monoxide pressure to produce propyl benzenes and, in three instances, chlorobutyrates.The isomer of propylbenzene obtained ranged from pure n-propylbenzene from PdCl2 to pure isopropylbenzene for OsCl3 and IrCl3.The other three platinum-metal chlorides gave mixture of the two propylbenzenes.The reaction was shown to be specific for benzene and cyclopropane as chlorobenzene and toluene failed to enter into the reaction.Likewise, methylcyclopropane did not react with benzene to produce butylbenzenes.