91132-63-7

Upstream product

• 106299-10-9 3,3-diethoxy-1-phenyl-propenone 
• 81471-31-0 3-oxo-3-phenyl-propionimidic acid ethyl ester; hydrochloride 
• 64-17-5 ethanol 
• 614-16-4 Benzoylacetonitrile 
• 16516-19-1 O-ethyl 3-oxo-3-phenylpropanethioate 
• 98-86-2 acetophenone 

Downstream Products

• 827-41-8 3-phenylpyrazol-5-amine 
• 126355-36-0 (4-Ethoxy-2-methyl-6-thioxo-1,6-dihydro-pyrimidin-5-yl)-phenyl-methanone 
• 3752-53-2 (4-ethoxy-2-phenyl-6-thioxo-1,6-dihydro-pyrimidin-5-yl)-phenyl-methanone 
• 79421-55-9 4-Oxo-2-phenacyl-4,5-dihydrothiazole 
• 126355-31-5 2-[(4-Chloro-phenyl)-hydrazono]-3-oxo-3-phenyl-propionimidic acid ethyl ester 
• 126355-33-7 2-[(4-Methoxy-phenyl)-hydrazono]-3-oxo-3-phenyl-propionimidic acid ethyl ester 
• 126355-32-6 3-Oxo-3-phenyl-2-(p-tolyl-hydrazono)-propionimidic acid ethyl ester 
• 126355-29-1 3-Oxo-3-phenyl-2-(phenyl-hydrazono)-propionimidic acid ethyl ester 
• 126355-30-4 2-Amino-5-benzoyl-4-phenyl-nicotinonitrile 
• 126355-34-8 2-Amino-5-benzoyl-4-(4-methoxy-phenyl)-nicotinonitrile 
• 94622-35-2 4-acetylamino-N-(5-phenyl-isoxazol-3-yl)-benzenesulfonamide 
• 93987-21-4 4-amino-N-(5-phenyl-isoxazol-3-yl)-benzenesulfonamide 
• 13273-63-7 3-acetamido-5-phenyl-isoxazole 
• 95515-91-6 Benzoylessigsaeure-O-acetyl-amidoxim 

Relevant academic research and scientific papers

Synthesis of aminopyrazoles from α- oxoketene O,N-acetals using Montmorillonite K-10/Ultrasound

5(3)-Amino-3(5) phenylpyrazoles 3a-f have been conveniently prepared by condensation of α-oxoketene O,N-acetals 2a-g with hydrazine using montmorillonite K-10 as solid support under sonication.

Synthesis of 5H-pyrido[2,3-c]-2-benzazepines

The title compounds can be obtained by two different ways: Ring closure of 2-benzazepine enaminonitrile 1 and the C2-building blocks 2, 7 and 8 gives rise to the title compounds 6, 9 and 10. - The second way starts with Wolff-Kishner-reduction of the 2-amino-3-benzoylpyridines 16a,b to the 2-amino-3-benzylpyridines 18a,b. Benzoylation of 18a,b leads to the dibenzoylated compounds 20 and 21, respectively, which can be transformed to the monobenzoylated pyridines 22 resp. 23. Applying the Bischler-Napieralski-reaction on 22a,b and 23a,b leads to the 5H-pyrido[2,3-c]-2-benzazepines 24a,b and 25a,b. By means of 1H-, 13C- and 15N-NMR-data it is demonstrated that ethyl benzoylcyanacetimidate (12a) exists as benzoylketene-O,N-acetal 12a AE.

Novel Synthesis of Polyfunctionally Substituted Pyridines and Pyrimidines

New syntheses of polyfunctionally substituted pyridines and pyrimidines by reaction of 3-amino-3-ethoxy-1-phenyl-2-propen-1-one with cinnamonitriles, or with acyl or aroyl isothiocyanates are reported.