91136-11-7Relevant academic research and scientific papers
AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES
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Paragraph 00190, (2017/02/09)
The invention relates to new compounds with low cytotoxicity for blocking the ubiquitination- proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers, neurodegenerative diseases, inflammatory disorders, autoimmune disorders and metabolic disorders.
Synthesis of 2-aryl-triazolo-pyrazines
Sambaiah, T,Reddy,K Kondal
, p. 444 - 445 (2007/10/02)
2-Aroylaminopyrazines (2), obtained by aroylation of 2-aminopyrazine (1), have been converted into 5-aryl-1-(2'-pyrazinyl)tetrazoles (4) by the reaction with PCl5 followed by treatment with sodium azide in aq. acetone.Pyrolysis of 4 in decalin results in
