91136-43-5 Usage
Uses
Used in Pharmaceutical Industry:
3-Hydroxynaphthalene-1-carboxaldehyde is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs.
Used in Dye Industry:
3-Hydroxynaphthalene-1-carboxaldehyde is used as an intermediate in the production of dyes, due to its chemical properties that facilitate the creation of color compounds.
Used in Fragrance Industry:
3-Hydroxynaphthalene-1-carboxaldehyde is used as an intermediate in the synthesis of fragrances, leveraging its aromatic properties to contribute to the development of scent compounds.
Used in Fluorescent Dye Production:
3-Hydroxynaphthalene-1-carboxaldehyde is used in the production of fluorescent dyes, taking advantage of its chemical structure to create dyes that emit light when excited.
Used as a Reagent in Chemical Analysis:
3-Hydroxynaphthalene-1-carboxaldehyde is used as a reagent in chemical analysis, serving as a valuable tool for detecting or measuring other substances in various chemical tests.
Safety Precautions:
3-Hydroxynaphthalene-1-carboxaldehyde is known to be a skin and eye irritant and may cause allergic reactions in some individuals. Therefore, proper safety precautions should be taken when handling this chemical to minimize potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 91136-43-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,1,3 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91136-43:
(7*9)+(6*1)+(5*1)+(4*3)+(3*6)+(2*4)+(1*3)=115
115 % 10 = 5
So 91136-43-5 is a valid CAS Registry Number.
91136-43-5Relevant academic research and scientific papers
Inhibition of Acyl-CoA: Cholesterol acyltransferase (ACAT), overexpression of cholesterol transporter gene, and protection of amyloid β (Aβ) oligomers-induced neuronal cell death by tricyclic pyrone molecules
Pokhrel, Laxman,Maezawa, Izumi,Nguyen, Thi D. T.,Chang, Kyeong-Ok,Jin, Lee-Way,Hua, Duy H.
, p. 8969 - 8973 (2013/01/15)
A major effort in Alzheimers disease therapeutic development has targeted Aβ and downstream events. We have synthesized a small library of tricyclic pyrone compounds. Their protective action in MC65 cells and inhibition of ACAT along with the upregulation of cholesterol transporter gene were investigated. Five active compounds exhibited potencies in the nanomolar ranges. The multiple effects of the compounds on Aβ and cellular cholesterol pathways could be potential mechanisms underlying the protective effects in vivo.
Synthesis and reactivity of formyl-substituted photochromic 3,3- diphenyl-[3H]-naphtho[2,1-b]pyrans
Chamontin, Karine,Lokshin, Vladimir,Rossollin, Valerie,Samat, Andre,Guglielmetti, Robert
, p. 5821 - 5830 (2007/10/03)
Synthetic accesses to formylated photochromic 3,3-diphenyl-[3H]- naphthopyrans (or 2H-benzochromenes) are developed through classical cyclization between appropriate hydroxynaphthaldehydes and 1,1- diphenylpropyne-1-ol and also via substituent transformations on the naphthopyran skeleton including bromine/lithium exchange and the oxidation of an hydroxymethyl group. Examples of formyl group reactivity (Wittig and Knoevenagel reactions, imine formation) from these compounds are given, showing their interest in the subsequent preparation of supramolecular systems involving a photoreactive entity.
